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Unfortunately up to 20% of individuals are non responders to GLP1s. This is not a YOU problem it is a limitation of the drug and should not be met with shame. #obesitymedicine #GLP1 # Weight Loss Shots at The Cove Med Spa Check out this clients progress on Semaglutide down 18 POUNDS! We offer Semaglutide + Tirzepatide weekly injections to help you reach your RCSB PDB 7KI0: Semaglutide bound Glucagon Like Peptide 1 (GLP 1) Receptor in Complex with Gs protein Key efficacy outcomes of the global PIONEER studies (PIONEER 15 and Download Scientific Diagram Is it OK to take tirzepatide a day early? Dosing flexibility
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.4 ★★★★★
Based on 276 reviews
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Product Reviews
★★★★★ 3
Brightens, doesn't firm
Color: Cyano Pink Spicule
I've been using this for about a month now, every night on my face and neck, hoping to reduce the appearance of wrinkles and tighten some of my skin in that area that seems to be losing elasticity. On my neck, I've honestly noticed no real difference in 4 weeks of continued, consistent daily use. The skin on my face does seem brighter and somewhat less textured than before, but I haven't noticed any change in the issues I was hoping this would resolve, based on the claims and how it was marketed. So... not a bad addition to my skincare, but not the solution I was looking for.
Some have expressed concerns about it tingling or stinging... You can feel something when you apply it, it's almost like the feeling of static electricity, but it's very mild. I wouldn't let that stop you from giving it a try if you were concerned about it. It didn't cause my sensitive skin any breakouts or redness (although I was applying it at night before bed, so perhaps any redness was calmed overnight). I'm going to go ahead and finish the bottle, but based on these results, I probably won't repurchase.
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Reviewed in the United States on May 3, 2026
★★★★★ 4
Decent Product
Color: Cyano Pink Spicule
Not bad for the $ , it makes my skin feel good.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Helped Tighten My Skin & Minimize Pores
Color: Cyano Pink Spicule, Color: Cyano Pink Spicule
I’ve loved the Dr. Melaxin Cyano Pink Spicule Serum! The bottle is small, but it lasted me around 6 months since I only use one pump every other night. When I first started using it, I noticed a tingling sensation, but over time my skin adjusted and I barely notice it now. I’ve definitely seen my pores appear smaller and my skin feels tighter and smoother after using it.
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Reviewed in the United States on May 26, 2026
★★★★★ 5
Great for pore reduction
Color: Cyano Pink Spicule
This product works great!! it almost feels like an exfoliator. It reduced the pours on my nose, which were very big and now you can barely see them. I would recommend this product if you have large pores also make skin look firmer and smoother more for a night cream though.
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Reviewed in the United States on May 31, 2026
★★★★★ 5
More than expected
Color: Cyano Pink Spicule
Love, love and recommended to friends. Leaves my skin feeling and looking great. At 69 I don't expect miracles but can definitely see an improvement in texture, glow and line minimizing. I'm hooked and will never be without!
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Reviewed in the United States on June 5, 2026
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